Homoarginine, Cardiovascular Risk, and Mortality

Homoarginine, kidney function and cardiovascular mortality risk.

BACKGROUND Homoarginine is a novel biomarker for cardiovascular diseases. In the present large cohort study, we evaluate how homoarginine is linked to kidney function and examine the potential interaction of homoarginine and kidney function as predictors of cardiovascular outcomes. METHODS Serum homoarginine (mean: 2.41 ± 1.05 µmol/L), cystatin C and creatinine-based estimated GFR (eGFR, mean...

Epidemiology and Prevention Homoarginine, Cardiovascular Risk, and Mortality

Background—Homoarginine is an amino acid derivative that may increase nitric oxide availability and enhance endothelial function. The effect of the level of homoarginine on cardiovascular outcome and mortality is unknown. Methods and Results—We assessed cardiovascular and all-cause mortality according to homoarginine levels in a cohort of 3305 subjects referred for coronary angiography from the...

Is homoarginine level associated with high cardiovascular risk and mortality?

L-homoarginine and cardiovascular disease.

PURPOSE OF REVIEW An increasing number of reports indicate that low levels of the endogenous amino acid L-homoarginine are linked to cardiovascular disease. In this article, we review the current findings regarding L-homoarginine metabolism and (patho-)physiology with a focus on its clinical impact. RECENT FINDINGS Recent clinical and epidemiological studies revealed a strong association of l...

Alcohol Consumption, Cardiovascular Risk Factors, and Mortality

Multivariate analysis of the association at baseline between problem drinking and cardiovascular risk factors among 1,233 white male employees of the Chicago Peoples Gas Company age 40-59 showed the 38 problem drinkers with significantly higher blood pressures and cigarette consumption and significantly lower relative weights than the others. Similar analyses among 1,899 white male employees of...